Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks

Hexavalent chromium [Cr(VI)] damages DNA and causes cancer, but it is unclear which DNA damage responses (DDRs) most critically protect cells from chromate toxicity. Here, genome-wide quantitative functional profiling, DDR measurements and genetic interaction assays in Schizosaccharomyces pombe reve...

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Detalles Bibliográficos
Autores principales: Ganguly, Abantika, Guo, Lan, Sun, Lingling, Suo, Fang, Du, Li-Lin, Russell, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128646/
https://www.ncbi.nlm.nih.gov/pubmed/30148840
http://dx.doi.org/10.1371/journal.pgen.1007595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128646/
https://www.ncbi.nlm.nih.gov/pubmed/30148840
http://dx.doi.org/10.1371/journal.pgen.1007595

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