Cargando…
Role of simple descriptors and applicability domain in predicting change in protein thermostability
The melting temperature (Tm) of a protein is the temperature at which half of the protein population is in a folded state. Therefore, Tm is a measure of the thermostability of a protein. Increasing the Tm of a protein is a critical goal in biotechnology and biomedicine. However, predicting the chang...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128648/ https://www.ncbi.nlm.nih.gov/pubmed/30192891 http://dx.doi.org/10.1371/journal.pone.0203819 |