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Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme
Synonymous mutations do not alter the specified amino acid but may alter the structure or function of an mRNA in ways that impact fitness. There are few examples in the literature, however, in which the effects of synonymous mutations on microbial growth rates have been measured, and even fewer for...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128649/ https://www.ncbi.nlm.nih.gov/pubmed/30148850 http://dx.doi.org/10.1371/journal.pgen.1007615 |