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Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells

Piezo1 is a mechanosensitive (MS) ion channel with characteristic fast-inactivation kinetics. We found a slowly-inactivating MS current in mouse embryonic stem (mES) cells and characterized it throughout their differentiation into motor-neurons to investigate its components. MS currents were large a...

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Detalles Bibliográficos
Autores principales:	del Mármol, Josefina Inés, Touhara, Kouki K, Croft, Gist, MacKinnon, Roderick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128688/ https://www.ncbi.nlm.nih.gov/pubmed/30132757 http://dx.doi.org/10.7554/eLife.33149

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