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A Single XLF Dimer Bridges DNA Ends During Non-Homologous End Joining

Non-homologous end joining (NHEJ) is the primary pathway of DNA double-strand break repair in vertebrate cells, yet it remains unclear how NHEJ factors assemble a synaptic complex that bridges DNA ends. To address the role of XRCC4-like factor (XLF) in synaptic complex assembly, we employed single-m...

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Detalles Bibliográficos
Autores principales:	Graham, Thomas G.W., Carney, Sean M., Walter, Johannes C., Loparo, Joseph J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128732/ https://www.ncbi.nlm.nih.gov/pubmed/30177755 http://dx.doi.org/10.1038/s41594-018-0120-y

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