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Structure and Gating Mechanism of the Transient Receptor Potential Channel TRPV3
The transient receptor potential (TRP) channel TRPV3 plays a crucial role in skin physiology and pathophysiology. Mutations in TRPV3 are associated with various skin diseases, including Olmsted syndrome, atopic dermatitis and rosacea. Here we present cryo-EM structures of full length mouse TRPV3 in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128766/ https://www.ncbi.nlm.nih.gov/pubmed/30127359 http://dx.doi.org/10.1038/s41594-018-0108-7 |