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Demethylator phenotypes in acute myeloid leukemia

Acute myeloid leukemia (AML) often harbors mutations in epigenetic regulators, and also has frequent DNA hypermethylation, including the presence of CpG island methylator phenotypes (CIMP). Although global hypomethylation is well-known in cancer, the question of whether distinct demethylator phenoty...

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Detalles Bibliográficos
Autores principales:	Kelly, Andrew D., Madzo, Jozef, Madireddi, Priyanka, Kropf, Patricia, Good, Charly R., Jelinek, Jaroslav, Issa, Jean-Pierre J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128790/ https://www.ncbi.nlm.nih.gov/pubmed/29556023 http://dx.doi.org/10.1038/s41375-018-0084-2

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