Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells

Currently, little is known about the evolution of epigenetic regulation in animal stem cells. Here we demonstrate, using the planarian stem cell system to investigate the role of the COMPASS family of MLL3/4 histone methyltransferases that their function as tumor suppressors in mammalian stem cells...

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Detalles Bibliográficos
Autores principales: Mihaylova, Yuliana, Abnave, Prasad, Kao, Damian, Hughes, Samantha, Lai, Alvina, Jaber-Hijazi, Farah, Kosaka, Nobuyoshi, Aboobaker, A. Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128892/
https://www.ncbi.nlm.nih.gov/pubmed/30194301
http://dx.doi.org/10.1038/s41467-018-06092-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128892/
https://www.ncbi.nlm.nih.gov/pubmed/30194301
http://dx.doi.org/10.1038/s41467-018-06092-6

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