Selective Deletion of Heparan Sulfotransferase Enzyme, Ndst1, in Donor Endothelial and Myeloid Precursor Cells Significantly Decreases Acute Allograft Rejection

Early damage to transplanted organs initiates excess inflammation that can cause ongoing injury, a leading cause for late graft loss. The endothelial glycocalyx modulates immune reactions and chemokine-mediated haptotaxis, potentially driving graft loss. In prior work, conditional deficiency of the...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Ambadapadi, Sriram, Wakefield, Dara, Bartee, Meeyong, Yaron, Jordan R., Zhang, Liqiang, Archer-Hartmann, Stephanie A., Azadi, Parastoo, Burgin, Michelle, Borges, Chad, Zheng, Donghang, Ergle, Kevin, Muppala, Vishnu, Morshed, Sufi, Rand, Kenneth, Clapp, William, Proudfoot, Amanda, Lucas, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128922/
https://www.ncbi.nlm.nih.gov/pubmed/30194334
http://dx.doi.org/10.1038/s41598-018-31779-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128922/
https://www.ncbi.nlm.nih.gov/pubmed/30194334
http://dx.doi.org/10.1038/s41598-018-31779-7

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