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Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions
In modern society, increasing people suffering from locomotor disabilities need an assistive exoskeleton to help them improve or restore ambulation. When walking is assisted by an exoskeleton, brain activities are altered as the closed-loop between brain and lower limbs is affected by the exoskeleto...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128944/ https://www.ncbi.nlm.nih.gov/pubmed/30194397 http://dx.doi.org/10.1038/s41598-018-31828-1 |
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author | Li, Junhua Thakor, Nitish Bezerianos, Anastasios |
author_facet | Li, Junhua Thakor, Nitish Bezerianos, Anastasios |
author_sort | Li, Junhua |
collection | PubMed |
description | In modern society, increasing people suffering from locomotor disabilities need an assistive exoskeleton to help them improve or restore ambulation. When walking is assisted by an exoskeleton, brain activities are altered as the closed-loop between brain and lower limbs is affected by the exoskeleton. Intuitively, a unilateral exoskeleton imposes differential effect on brain hemispheres (i.e., hemispherical effect) according to contralateral control mechanism. However, it is unclear whether hemispherical effect appears in whole hemisphere or particular region. To this end, we explored hemispherical effect on different brain regions using EEG data collected from 30 healthy participants during overground walking. The results showed that hemispherical effect was significantly different between regions when a unilateral exoskeleton was employed for walking assistance and no significance was observed for walking without the exoskeleton. Post-hoc t-test analysis revealed that hemispherical effect in the parietooccipital region significantly differed from other regions. In the parietooccipital region, a greater hemispherical effect was observed in beta band for exoskeleton-assisted walking compared to walking without exoskeleton, which was also found in the source analysis. These findings deepen the understanding of hemispherical effect of unilateral exoskeleton on brain and could aid the development of more efficient and suitable exoskeleton for walking assistance. |
format | Online Article Text |
id | pubmed-6128944 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61289442018-09-10 Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions Li, Junhua Thakor, Nitish Bezerianos, Anastasios Sci Rep Article In modern society, increasing people suffering from locomotor disabilities need an assistive exoskeleton to help them improve or restore ambulation. When walking is assisted by an exoskeleton, brain activities are altered as the closed-loop between brain and lower limbs is affected by the exoskeleton. Intuitively, a unilateral exoskeleton imposes differential effect on brain hemispheres (i.e., hemispherical effect) according to contralateral control mechanism. However, it is unclear whether hemispherical effect appears in whole hemisphere or particular region. To this end, we explored hemispherical effect on different brain regions using EEG data collected from 30 healthy participants during overground walking. The results showed that hemispherical effect was significantly different between regions when a unilateral exoskeleton was employed for walking assistance and no significance was observed for walking without the exoskeleton. Post-hoc t-test analysis revealed that hemispherical effect in the parietooccipital region significantly differed from other regions. In the parietooccipital region, a greater hemispherical effect was observed in beta band for exoskeleton-assisted walking compared to walking without exoskeleton, which was also found in the source analysis. These findings deepen the understanding of hemispherical effect of unilateral exoskeleton on brain and could aid the development of more efficient and suitable exoskeleton for walking assistance. Nature Publishing Group UK 2018-09-07 /pmc/articles/PMC6128944/ /pubmed/30194397 http://dx.doi.org/10.1038/s41598-018-31828-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Li, Junhua Thakor, Nitish Bezerianos, Anastasios Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions |
title | Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions |
title_full | Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions |
title_fullStr | Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions |
title_full_unstemmed | Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions |
title_short | Unilateral Exoskeleton Imposes Significantly Different Hemispherical Effect in Parietooccipital Region, but Not in Other Regions |
title_sort | unilateral exoskeleton imposes significantly different hemispherical effect in parietooccipital region, but not in other regions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128944/ https://www.ncbi.nlm.nih.gov/pubmed/30194397 http://dx.doi.org/10.1038/s41598-018-31828-1 |
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