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Numerical investigation of the blood flow through the middle cerebral artery
[Image: see text] Introduction: The middle cerebral artery (MCA) is one of the three major paired arteries that supply the blood to the cerebrum. In the present study, the three-dimensional (3D) blood flow in the left MCA was numerically simulated by using the medical imaging. Methods: The arterial...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128971/ https://www.ncbi.nlm.nih.gov/pubmed/30211079 http://dx.doi.org/10.15171/bi.2018.22 |
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author | Razavi, Seyed Esmail Farhangmehr, Vahid Zendeali, Nafiseh |
author_facet | Razavi, Seyed Esmail Farhangmehr, Vahid Zendeali, Nafiseh |
author_sort | Razavi, Seyed Esmail |
collection | PubMed |
description | [Image: see text] Introduction: The middle cerebral artery (MCA) is one of the three major paired arteries that supply the blood to the cerebrum. In the present study, the three-dimensional (3D) blood flow in the left MCA was numerically simulated by using the medical imaging. Methods: The arterial geometry was obtained by applying the CT angiography of the MCA of a 75-year-old man. The blood flow was assumed to be laminar and unsteady. Numerical simulations were done by commercial software package COMSOL Multiphysics 5.2. In this software, the Galerkin’s finite element method was applied to solve the governing equations. Results: It was found that the results obtained for the Newtonian and non-Newtonian models of blood do not differ from each other significantly. Thus, the Newtonian model for blood flow in the MCA is acceptable. Also, the most susceptible region of the MCA for Atherosclerosis was detected. Conclusion: It can be concluded that the application of the Newtonian model for the blood flowing in the MCA is acceptable. Also, atherosclerosis has the potential to occur at the middle of a branch of the MCA which has the highest geometrical curvature. |
format | Online Article Text |
id | pubmed-6128971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-61289712018-09-12 Numerical investigation of the blood flow through the middle cerebral artery Razavi, Seyed Esmail Farhangmehr, Vahid Zendeali, Nafiseh Bioimpacts Original Research [Image: see text] Introduction: The middle cerebral artery (MCA) is one of the three major paired arteries that supply the blood to the cerebrum. In the present study, the three-dimensional (3D) blood flow in the left MCA was numerically simulated by using the medical imaging. Methods: The arterial geometry was obtained by applying the CT angiography of the MCA of a 75-year-old man. The blood flow was assumed to be laminar and unsteady. Numerical simulations were done by commercial software package COMSOL Multiphysics 5.2. In this software, the Galerkin’s finite element method was applied to solve the governing equations. Results: It was found that the results obtained for the Newtonian and non-Newtonian models of blood do not differ from each other significantly. Thus, the Newtonian model for blood flow in the MCA is acceptable. Also, the most susceptible region of the MCA for Atherosclerosis was detected. Conclusion: It can be concluded that the application of the Newtonian model for the blood flowing in the MCA is acceptable. Also, atherosclerosis has the potential to occur at the middle of a branch of the MCA which has the highest geometrical curvature. Tabriz University of Medical Sciences 2018 2018-05-10 /pmc/articles/PMC6128971/ /pubmed/30211079 http://dx.doi.org/10.15171/bi.2018.22 Text en © 2018 The Author(s) This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Original Research Razavi, Seyed Esmail Farhangmehr, Vahid Zendeali, Nafiseh Numerical investigation of the blood flow through the middle cerebral artery |
title | Numerical investigation of the blood flow through the middle cerebral artery |
title_full | Numerical investigation of the blood flow through the middle cerebral artery |
title_fullStr | Numerical investigation of the blood flow through the middle cerebral artery |
title_full_unstemmed | Numerical investigation of the blood flow through the middle cerebral artery |
title_short | Numerical investigation of the blood flow through the middle cerebral artery |
title_sort | numerical investigation of the blood flow through the middle cerebral artery |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128971/ https://www.ncbi.nlm.nih.gov/pubmed/30211079 http://dx.doi.org/10.15171/bi.2018.22 |
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