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Numerical investigation of the blood flow through the middle cerebral artery

[Image: see text] Introduction: The middle cerebral artery (MCA) is one of the three major paired arteries that supply the blood to the cerebrum. In the present study, the three-dimensional (3D) blood flow in the left MCA was numerically simulated by using the medical imaging. Methods: The arterial...

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Autores principales: Razavi, Seyed Esmail, Farhangmehr, Vahid, Zendeali, Nafiseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128971/
https://www.ncbi.nlm.nih.gov/pubmed/30211079
http://dx.doi.org/10.15171/bi.2018.22
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author Razavi, Seyed Esmail
Farhangmehr, Vahid
Zendeali, Nafiseh
author_facet Razavi, Seyed Esmail
Farhangmehr, Vahid
Zendeali, Nafiseh
author_sort Razavi, Seyed Esmail
collection PubMed
description [Image: see text] Introduction: The middle cerebral artery (MCA) is one of the three major paired arteries that supply the blood to the cerebrum. In the present study, the three-dimensional (3D) blood flow in the left MCA was numerically simulated by using the medical imaging. Methods: The arterial geometry was obtained by applying the CT angiography of the MCA of a 75-year-old man. The blood flow was assumed to be laminar and unsteady. Numerical simulations were done by commercial software package COMSOL Multiphysics 5.2. In this software, the Galerkin’s finite element method was applied to solve the governing equations. Results: It was found that the results obtained for the Newtonian and non-Newtonian models of blood do not differ from each other significantly. Thus, the Newtonian model for blood flow in the MCA is acceptable. Also, the most susceptible region of the MCA for Atherosclerosis was detected. Conclusion: It can be concluded that the application of the Newtonian model for the blood flowing in the MCA is acceptable. Also, atherosclerosis has the potential to occur at the middle of a branch of the MCA which has the highest geometrical curvature.
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spelling pubmed-61289712018-09-12 Numerical investigation of the blood flow through the middle cerebral artery Razavi, Seyed Esmail Farhangmehr, Vahid Zendeali, Nafiseh Bioimpacts Original Research [Image: see text] Introduction: The middle cerebral artery (MCA) is one of the three major paired arteries that supply the blood to the cerebrum. In the present study, the three-dimensional (3D) blood flow in the left MCA was numerically simulated by using the medical imaging. Methods: The arterial geometry was obtained by applying the CT angiography of the MCA of a 75-year-old man. The blood flow was assumed to be laminar and unsteady. Numerical simulations were done by commercial software package COMSOL Multiphysics 5.2. In this software, the Galerkin’s finite element method was applied to solve the governing equations. Results: It was found that the results obtained for the Newtonian and non-Newtonian models of blood do not differ from each other significantly. Thus, the Newtonian model for blood flow in the MCA is acceptable. Also, the most susceptible region of the MCA for Atherosclerosis was detected. Conclusion: It can be concluded that the application of the Newtonian model for the blood flowing in the MCA is acceptable. Also, atherosclerosis has the potential to occur at the middle of a branch of the MCA which has the highest geometrical curvature. Tabriz University of Medical Sciences 2018 2018-05-10 /pmc/articles/PMC6128971/ /pubmed/30211079 http://dx.doi.org/10.15171/bi.2018.22 Text en © 2018 The Author(s) This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Research
Razavi, Seyed Esmail
Farhangmehr, Vahid
Zendeali, Nafiseh
Numerical investigation of the blood flow through the middle cerebral artery
title Numerical investigation of the blood flow through the middle cerebral artery
title_full Numerical investigation of the blood flow through the middle cerebral artery
title_fullStr Numerical investigation of the blood flow through the middle cerebral artery
title_full_unstemmed Numerical investigation of the blood flow through the middle cerebral artery
title_short Numerical investigation of the blood flow through the middle cerebral artery
title_sort numerical investigation of the blood flow through the middle cerebral artery
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128971/
https://www.ncbi.nlm.nih.gov/pubmed/30211079
http://dx.doi.org/10.15171/bi.2018.22
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