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FOXM1 contributes to treatment failure in acute myeloid leukemia
Acute myeloid leukemia (AML) patients with NPM1 mutations demonstrate a superior response to standard chemotherapy treatment. Our previous work has shown that these favorable outcomes are linked to the cytoplasmic relocalization and inactivation of FOXM1 driven by mutated NPM1. Here, we went on to c...
Autores principales: | Khan, Irum, Halasi, Marianna, Patel, Anand, Schultz, Rachael, Kalakota, Nandini, Chen, Yi-Hua, Aardsma, Nathan, Liu, Li, Crispino, John D., Mahmud, Nadim, Frankfurt, Olga, Gartel, Andrei L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129129/ https://www.ncbi.nlm.nih.gov/pubmed/30089730 http://dx.doi.org/10.1172/jci.insight.121583 |
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