Cargando…

Experimental Microbial Dysbiosis Does Not Promote Disease Progression in SIV-Infected Macaques

Intestinal microbial dysbiosis has been described in HIV-1-infected individuals and may underlie persistent inflammation in chronic infection, thereby contributing to disease progression. Herein, we induced an HIV-1-like intestinal dysbiosis in rhesus macaques with vancomycin treatment and assessed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ortiz, Alexandra M., Flynn, Jacob K., DiNapoli, Sarah R., Vujkovic-Cvijin, Ivan, Starke, Carly Elizabeth C., Lai, Stephen H., Long, MacKenzie E., Sortino, Ornella, Vinton, Carol L., Mudd, Joseph C., Johnston, Leslie, Busman-Sahay, Kathleen, Belkaid, Yasmine, Estes, Jacob D., Brenchley, Jason M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129204/ https://www.ncbi.nlm.nih.gov/pubmed/30061696 http://dx.doi.org/10.1038/s41591-018-0132-5

Ejemplares similares

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility
por: Ortiz, Alexandra M., et al.
Publicado: (2023)

IL-21 and Probiotic Therapy Improve T(H)17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques
por: Ortiz, Alexandra M., et al.
Publicado: (2015)

Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo
por: Vinton, Carol L., et al.
Publicado: (2020)

HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases
por: Vujkovic-Cvijin, I., et al.
Publicado: (2020)

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques
por: Ortiz, Alexandra M., et al.
Publicado: (2022)

Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments
por: Deleage, Claire, et al.
Publicado: (2018)

Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys
por: Mudd, Joseph C., et al.
Publicado: (2020)

Dysbiotic Bacteria Translocate in Progressive SIV Infection
por: Klase, Zachary, et al.
Publicado: (2015)

Host variables confound gut microbiota studies of human disease
por: Vujkovic-Cvijin, Ivan, et al.
Publicado: (2020)

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection
por: Hao, Xing Pei, et al.
Publicado: (2015)

Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation and IL-17 production in the absence of SIV infection
por: Klatt, Nichole R., et al.
Publicado: (2010)

Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques
por: Byrnes, Sarah J., et al.
Publicado: (2023)

Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
por: Mudd, Joseph C., et al.
Publicado: (2018)

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
por: Harper, Justin, et al.
Publicado: (2022)

Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques
por: Bochart, Rachele M., et al.
Publicado: (2021)

Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques
por: Aid, Malika, et al.
Publicado: (2022)

“METAGENOTE: a simplified web platform for metadata annotation of genomic samples and streamlined submission to NCBI’s sequence read archive”
por: Quiñones, Mariam, et al.
Publicado: (2020)

Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques
por: Bochart, Rachele M., et al.
Publicado: (2023)

P11-01. Extensive intestinal damage underlies microbial translocation in the GI tract of chronically SIV-infected Rhesus macaques
por: Harris, LD, et al.
Publicado: (2009)

Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection
por: Klatt, Nichole R., et al.
Publicado: (2012)

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance
por: Vinton, Carol L., et al.
Publicado: (2019)

Transcription Profiling Reveals Potential Mechanisms of Dysbiosis in the Oral Microbiome of Rhesus Macaques with Chronic Untreated SIV Infection
por: Ocon, Susan, et al.
Publicado: (2013)

Liver Bacterial Dysbiosis With Non-Tuberculosis Mycobacteria Occurs in SIV-Infected Macaques and Persists During Antiretroviral Therapy
por: Fisher, Bridget S., et al.
Publicado: (2022)

Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2011)

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV
por: Marshall, Vickie A., et al.
Publicado: (2018)

Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2018)

African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity
por: Raehtz, Kevin D., et al.
Publicado: (2020)

The Impact of Anthelmintic Treatment on Human Gut Microbiota Based on Cross-Sectional and Pre- and Postdeworming Comparisons in Western Kenya
por: Easton, Alice V., et al.
Publicado: (2019)

SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Mycobacterium tuberculosis Co-Infection
por: Tisthammer, Kaho H., et al.
Publicado: (2021)

Visualizing the Immune System: Providing Key Insights into HIV/SIV Infections
por: Estes, Jacob D., et al.
Publicado: (2018)

Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques
por: Srinivasula, Sharat, et al.
Publicado: (2023)

Profiling the airway in the macaque model of tuberculosis reveals variable microbial dysbiosis and alteration of community structure
por: Cadena, Anthony M, et al.
Publicado: (2018)

Increased neutrophil apoptosis in chronically SIV-infected macaques
por: Elbim, Carole, et al.
Publicado: (2009)

MHC and KIR Polymorphisms in Rhesus Macaque SIV Infection
por: Walter, Lutz, et al.
Publicado: (2015)

Maintenance of Intestinal Th17 Cells and Reduced Microbial Translocation in SIV-infected Rhesus Macaques Treated with Interleukin (IL)-21
por: Pallikkuth, Suresh, et al.
Publicado: (2013)

CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells
por: Micci, Luca, et al.
Publicado: (2014)

Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques
por: Aid, Malika, et al.
Publicado: (2020)

Feasibility and safety of ultrasound-guided minimally invasive autopsy in COVID-19 patients
por: Brook, Olga R., et al.
Publicado: (2020)

Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques
por: Couturier, Jacob, et al.
Publicado: (2016)

IL-2 immunotherapy in chronically SIV-infected Rhesus Macaques
por: Garibal, Julie, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_gkg0g15ckp2adc34lj5guu6s13