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Amputation stump perfusion is predictive of post-operative necrotic eschar formation

BACKGROUND: A large proportion of patients develop poor amputation stump healing. We hypothesize that Laser-Assisted Fluorescent Angiography (LAFA) can predict inadequate tissue perfusion and healing. METHODS: Over an 8-month period we reviewed all patients who underwent lower extremity amputation a...

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Detalles Bibliográficos
Autores principales: De Silva, Gayan S., Saffaf, Khalid, Sanchez, Luis A., Zayed, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129216/
https://www.ncbi.nlm.nih.gov/pubmed/29789123
http://dx.doi.org/10.1016/j.amjsurg.2018.05.007
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author De Silva, Gayan S.
Saffaf, Khalid
Sanchez, Luis A.
Zayed, Mohamed A.
author_facet De Silva, Gayan S.
Saffaf, Khalid
Sanchez, Luis A.
Zayed, Mohamed A.
author_sort De Silva, Gayan S.
collection PubMed
description BACKGROUND: A large proportion of patients develop poor amputation stump healing. We hypothesize that Laser-Assisted Fluorescent Angiography (LAFA) can predict inadequate tissue perfusion and healing. METHODS: Over an 8-month period we reviewed all patients who underwent lower extremity amputation and LAFA. We evaluated intra-operative LAFA global and segmental stump perfusion, and post-operative modified Bates-Jensen (mBJS) wound healing scores. RESULTS: In 15 patients, amputation stumps with lower global perfusion demonstrated higher mBJS (P = 0.01). Lower suture-line perfusion also correlated with more eschar formation (P < 0.001). Diabetic patients had higher mBJS (P = 0.009), lower stump perfusion (P = 0.02), and increased eschar volume (P < 0.001). CONCLUSION: LAFA is a useful adjunct for intra-operative stump perfusion assessment and can predict areas of poor stump healing and eschar formation. Diabetic patients seem to be at higher risk of stump eschar formation.
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spelling pubmed-61292162019-09-01 Amputation stump perfusion is predictive of post-operative necrotic eschar formation De Silva, Gayan S. Saffaf, Khalid Sanchez, Luis A. Zayed, Mohamed A. Am J Surg Article BACKGROUND: A large proportion of patients develop poor amputation stump healing. We hypothesize that Laser-Assisted Fluorescent Angiography (LAFA) can predict inadequate tissue perfusion and healing. METHODS: Over an 8-month period we reviewed all patients who underwent lower extremity amputation and LAFA. We evaluated intra-operative LAFA global and segmental stump perfusion, and post-operative modified Bates-Jensen (mBJS) wound healing scores. RESULTS: In 15 patients, amputation stumps with lower global perfusion demonstrated higher mBJS (P = 0.01). Lower suture-line perfusion also correlated with more eschar formation (P < 0.001). Diabetic patients had higher mBJS (P = 0.009), lower stump perfusion (P = 0.02), and increased eschar volume (P < 0.001). CONCLUSION: LAFA is a useful adjunct for intra-operative stump perfusion assessment and can predict areas of poor stump healing and eschar formation. Diabetic patients seem to be at higher risk of stump eschar formation. 2018-05-19 2018-09 /pmc/articles/PMC6129216/ /pubmed/29789123 http://dx.doi.org/10.1016/j.amjsurg.2018.05.007 Text en This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
De Silva, Gayan S.
Saffaf, Khalid
Sanchez, Luis A.
Zayed, Mohamed A.
Amputation stump perfusion is predictive of post-operative necrotic eschar formation
title Amputation stump perfusion is predictive of post-operative necrotic eschar formation
title_full Amputation stump perfusion is predictive of post-operative necrotic eschar formation
title_fullStr Amputation stump perfusion is predictive of post-operative necrotic eschar formation
title_full_unstemmed Amputation stump perfusion is predictive of post-operative necrotic eschar formation
title_short Amputation stump perfusion is predictive of post-operative necrotic eschar formation
title_sort amputation stump perfusion is predictive of post-operative necrotic eschar formation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129216/
https://www.ncbi.nlm.nih.gov/pubmed/29789123
http://dx.doi.org/10.1016/j.amjsurg.2018.05.007
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AT zayedmohameda amputationstumpperfusionispredictiveofpostoperativenecroticescharformation