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An ontology-based method for assessing batch effect adjustment approaches in heterogeneous datasets

MOTIVATION: International consortia such as the Genotype-Tissue Expression (GTEx) project, The Cancer Genome Atlas (TCGA) or the International Human Epigenetics Consortium (IHEC) have produced a wealth of genomic datasets with the goal of advancing our understanding of cell differentiation and disea...

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Detalles Bibliográficos
Autores principales: Schmidt, Florian, List, Markus, Cukuroglu, Engin, Köhler, Sebastian, Göke, Jonathan, Schulz, Marcel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129283/
https://www.ncbi.nlm.nih.gov/pubmed/30423059
http://dx.doi.org/10.1093/bioinformatics/bty553