Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue

Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adu...

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Detalles Bibliográficos
Autores principales: Tomokiyo, Atsushi, Yoshida, Shinichiro, Hamano, Sayuri, Hasegawa, Daigaku, Sugii, Hideki, Maeda, Hidefumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129323/
https://www.ncbi.nlm.nih.gov/pubmed/30224921
http://dx.doi.org/10.1155/2018/5450768
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author Tomokiyo, Atsushi
Yoshida, Shinichiro
Hamano, Sayuri
Hasegawa, Daigaku
Sugii, Hideki
Maeda, Hidefumi
author_facet Tomokiyo, Atsushi
Yoshida, Shinichiro
Hamano, Sayuri
Hasegawa, Daigaku
Sugii, Hideki
Maeda, Hidefumi
author_sort Tomokiyo, Atsushi
collection PubMed
description Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.
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spelling pubmed-61293232018-09-17 Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue Tomokiyo, Atsushi Yoshida, Shinichiro Hamano, Sayuri Hasegawa, Daigaku Sugii, Hideki Maeda, Hidefumi Stem Cells Int Review Article Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration. Hindawi 2018-08-26 /pmc/articles/PMC6129323/ /pubmed/30224921 http://dx.doi.org/10.1155/2018/5450768 Text en Copyright © 2018 Atsushi Tomokiyo et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tomokiyo, Atsushi
Yoshida, Shinichiro
Hamano, Sayuri
Hasegawa, Daigaku
Sugii, Hideki
Maeda, Hidefumi
Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
title Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
title_full Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
title_fullStr Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
title_full_unstemmed Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
title_short Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
title_sort detection, characterization, and clinical application of mesenchymal stem cells in periodontal ligament tissue
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129323/
https://www.ncbi.nlm.nih.gov/pubmed/30224921
http://dx.doi.org/10.1155/2018/5450768
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