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Genomic Subtypes of GISTs for Stratifying Patient Response to Sunitinib following Imatinib Resistance: A Pooled Analysis and Systematic Review

OBJECTIVES: Sunitinib (a second-line chemotherapeutic agent that inhibits multiple kinases, including KIT and PDGFR) is widely used in imatinib-resistant patients with gastrointestinal stromal tumors (GISTs). However, diverse responses to sunitinib have been observed in the clinic. We aimed to evalu...

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Detalles Bibliográficos
Autores principales:	Tan, Siyuan, Chen, Ping, Ji, Jiafu, Guo, Shanshan, Yu, Dapeng, Asakawa, Tetsuya, Zhou, Yu, Abe, Masanobu, Zong, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129330/ https://www.ncbi.nlm.nih.gov/pubmed/30224936 http://dx.doi.org/10.1155/2018/1368617

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