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miR-125a Suppresses TrxR1 Expression and Is Involved in H(2)O(2)-Induced Oxidative Stress in Endothelial Cells

Thioredoxin reductase (TrxR), an antioxidant enzyme dependent on nicotinamide adenine dinucleotide phosphate, plays a vital role in defense against oxidative stress. However, the role of microRNAs targeting TrxR under oxidative stress has not yet been determined. In this study, we tested the involve...

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Detalles Bibliográficos
Autores principales: Chen, Fangjie, Liu, Hong, Wu, Jingjing, Zhao, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129346/
https://www.ncbi.nlm.nih.gov/pubmed/30225271
http://dx.doi.org/10.1155/2018/6140320