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Venetoclax in Combination with Decitabine for Relapsed T-Cell Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Cell Transplant

Long-term disease-free survival in adults with T-cell acute lymphoblastic leukemia (T-ALL) remains poor, particularly after relapse, with few available salvage options. Preclinical data suggest that inhibition of the antiapoptotic protein BCL-2 (B-cell lymphoma 2) either alone or in combination with...

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Detalles Bibliográficos
Autores principales: Rahmat, Leena T., Nguyen, Anna, Abdulhaq, Haifaa, Prakash, Sonam, Logan, Aaron C., Mannis, Gabriel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129347/
https://www.ncbi.nlm.nih.gov/pubmed/30225152
http://dx.doi.org/10.1155/2018/6092646