Antigen Uptake by Langerhans Cells Is Required for the Induction of Regulatory T Cells and the Acquisition of Tolerance During Epicutaneous Immunotherapy in OVA-Sensitized Mice

The skin is a major immunologic organ that may induce protection, sensitization or tolerance. Epicutaneous immunotherapy (EPIT) has been proposed as an attractive strategy to actively treat food allergy and has been shown to induce tolerance in sensitized mice through the induction of Foxp3(+) regul...

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Detalles Bibliográficos
Autores principales: Dioszeghy, Vincent, Mondoulet, Lucie, Laoubi, Leo, Dhelft, Véronique, Plaquet, Camille, Bouzereau, Adeline, Dupont, Christophe, Sampson, Hugh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129590/
https://www.ncbi.nlm.nih.gov/pubmed/30233572
http://dx.doi.org/10.3389/fimmu.2018.01951

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