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Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of patients with sporadic Alzheimer's disease
In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage is also present in patients’ peripheral tissues, suggesting a target to develop new biomarkers...
Autores principales: | Pérez, María José, Ponce, Daniela P., Aranguiz, Alejandra, Behrens, Maria I., Quintanilla, Rodrigo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129674/ https://www.ncbi.nlm.nih.gov/pubmed/30199818 http://dx.doi.org/10.1016/j.redox.2018.09.001 |
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