Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia

Patients with haematological malignancy are often profoundly immune suppressed, and more so if they require more than one line of therapy. Infection should always be considered when they become unwell. We discuss the differential diagnoses of a young man with multiply-relapsed Philadelphia chromosom...

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Detalles Bibliográficos
Autores principales: Lofaro, Thomas, Saha, Aritra, Raj, Kavita, Dillon, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129732/
https://www.ncbi.nlm.nih.gov/pubmed/30202728
http://dx.doi.org/10.1016/j.idcr.2018.e00447
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author Lofaro, Thomas
Saha, Aritra
Raj, Kavita
Dillon, Richard
author_facet Lofaro, Thomas
Saha, Aritra
Raj, Kavita
Dillon, Richard
author_sort Lofaro, Thomas
collection PubMed
description Patients with haematological malignancy are often profoundly immune suppressed, and more so if they require more than one line of therapy. Infection should always be considered when they become unwell. We discuss the differential diagnoses of a young man with multiply-relapsed Philadelphia chromosome-positive B-cell acute lymphoblastic leukaemia who presented with neurological symptoms and cerebrospinal fluid lymphocytosis. The diagnostic approach needs to be rapid and structured, and may require microbiology and neurology support.
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spelling pubmed-61297322018-09-10 Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia Lofaro, Thomas Saha, Aritra Raj, Kavita Dillon, Richard IDCases Article Patients with haematological malignancy are often profoundly immune suppressed, and more so if they require more than one line of therapy. Infection should always be considered when they become unwell. We discuss the differential diagnoses of a young man with multiply-relapsed Philadelphia chromosome-positive B-cell acute lymphoblastic leukaemia who presented with neurological symptoms and cerebrospinal fluid lymphocytosis. The diagnostic approach needs to be rapid and structured, and may require microbiology and neurology support. Elsevier 2018-08-31 /pmc/articles/PMC6129732/ /pubmed/30202728 http://dx.doi.org/10.1016/j.idcr.2018.e00447 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Lofaro, Thomas
Saha, Aritra
Raj, Kavita
Dillon, Richard
Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia
title Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia
title_full Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia
title_fullStr Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia
title_full_unstemmed Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia
title_short Non-malignant CSF lymphocytosis in a patient with acute lymphoblastic leukemia
title_sort non-malignant csf lymphocytosis in a patient with acute lymphoblastic leukemia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129732/
https://www.ncbi.nlm.nih.gov/pubmed/30202728
http://dx.doi.org/10.1016/j.idcr.2018.e00447
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