Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

BACKGROUND: Ovarian cancer is considered one of the lethal cancers responsible for high mortality and morbidity across the world. The prognosis and the survival rate of ovarian cancer is far from decent. Cysteine-rich 61 (Cyr61) also known as CCN1, is a member of CCN-family of growth factors, report...

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Detalles Bibliográficos
Autores principales: Zhang, Fengli, Chen, Huixiao, Du, Jing, Wang, Bin, Yang, Lixiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130173/
https://www.ncbi.nlm.nih.gov/pubmed/30171812
http://dx.doi.org/10.12659/MSM.909745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130173/
https://www.ncbi.nlm.nih.gov/pubmed/30171812
http://dx.doi.org/10.12659/MSM.909745

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