TET family dioxygenases and DNA demethylation in stem cells and cancers

The methylation of cytosine and subsequent oxidation constitutes a fundamental epigenetic modification in mammalian genomes, and its abnormalities are intimately coupled to various pathogenic processes including cancer development. Enzymes of the Ten–eleven translocation (TET) family catalyze the st...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Jungeun, Rao, Anjana, Ko, Myunggon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130217/
https://www.ncbi.nlm.nih.gov/pubmed/28450733
http://dx.doi.org/10.1038/emm.2017.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130217/
https://www.ncbi.nlm.nih.gov/pubmed/28450733
http://dx.doi.org/10.1038/emm.2017.5

Ejemplares similares