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TET family dioxygenases and DNA demethylation in stem cells and cancers

The methylation of cytosine and subsequent oxidation constitutes a fundamental epigenetic modification in mammalian genomes, and its abnormalities are intimately coupled to various pathogenic processes including cancer development. Enzymes of the Ten–eleven translocation (TET) family catalyze the st...

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Detalles Bibliográficos
Autores principales:	An, Jungeun, Rao, Anjana, Ko, Myunggon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130217/ https://www.ncbi.nlm.nih.gov/pubmed/28450733 http://dx.doi.org/10.1038/emm.2017.5

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