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Inhibition of Glycolysis Reduces Disease Severity in an Autoimmune Model of Rheumatoid Arthritis

The K/BxN mouse is a spontaneous model of arthritis driven by T cell receptor transgenic CD4(+) T cells from the KRN strain that are activated by glucose-6-phosphate isomerase (GPI) peptides presented by the H-2(g7) allele from the NOD strain. It is a model of autoimmune seropositive arthritis becau...

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Detalles Bibliográficos
Autores principales:	Abboud, Georges, Choi, Seung-Chul, Kanda, Nathalie, Zeumer-Spataro, Leilani, Roopenian, Derry C., Morel, Laurence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130222/ https://www.ncbi.nlm.nih.gov/pubmed/30233578 http://dx.doi.org/10.3389/fimmu.2018.01973

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