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Systemic Candidiasis and TLR2 Agonist Exposure Impact the Antifungal Response of Hematopoietic Stem and Progenitor Cells

We have previously demonstrated that Candida albicans induces differentiation of hematopoietic stem and progenitor cells (HSPCs) toward the myeloid lineage both in vitro and in vivo in a TLR2- and Dectin-1-dependent manner, giving rise to functional macrophages. In this work, we used an ex vivo mode...

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Detalles Bibliográficos
Autores principales:	Martínez, Alba, Bono, Cristina, Megías, Javier, Yáñez, Alberto, Gozalbo, Daniel, Gil, M. Luisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130230/ https://www.ncbi.nlm.nih.gov/pubmed/30234030 http://dx.doi.org/10.3389/fcimb.2018.00309

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