Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal Mice

Pemphigus vulgaris (PV) is a potentially life-threatening autoimmune blistering disease which is associated with autoantibodies directed against two desmosomal proteins, desmoglein (Dsg) 3 and 1. Treatment of PV is rather challenging and relies on the long-term use of systemic corticosteroids and ad...

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Detalles Bibliográficos
Autores principales: Hofrichter, Maxi, Dworschak, Jenny, Emtenani, Shirin, Langenhan, Jana, Weiß, Fanny, Komorowski, Lars, Zillikens, Detlef, Stöcker, Winfried, Probst, Christian, Schmidt, Enno, Goletz, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130267/
https://www.ncbi.nlm.nih.gov/pubmed/30233569
http://dx.doi.org/10.3389/fimmu.2018.01935

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