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The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order
Cryocooling of macromolecular crystals is commonly employed to limit radiation damage during X-ray diffraction data collection. However, cooling itself affects macromolecular conformation and often damages crystals via poorly understood processes. Here, the effects of cryosolution thermal contractio...
Autores principales: | Juers, Douglas H., Farley, Christopher A., Saxby, Christopher P., Cotter, Rosemary A., Cahn, Jackson K. B., Holton-Burke, R. Conor, Harrison, Kaitlin, Wu, Zhenguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130464/ https://www.ncbi.nlm.nih.gov/pubmed/30198901 http://dx.doi.org/10.1107/S2059798318008793 |
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