Cargando…

Inhibition of key enzymes linked to type 2 diabetes by compounds isolated from Aframomum melegueta fruit

Context: The use of Aframomum melegueta K. Schum. (Zingiberaceae) fruit for treatment of diabetes has recently been established in Nigeria. However, compounds responsible for the antidiabetic action have not been identified. Objective: The present study carried out the bioassay-guided isolation of p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohammed, Aminu, Gbonjubola, Victoria Awolola, Koorbanally, Neil Anthony, Islam, Md. Shahidul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130490/ https://www.ncbi.nlm.nih.gov/pubmed/28176546 http://dx.doi.org/10.1080/13880209.2017.1286358

Ejemplares similares

In situ morphometric characterization of Aframomum melegueta accessions in Ghana
por: Amponsah, J., et al.
Publicado: (2013)

Anti-inflammatory Activity of Grains of Paradise (Aframomum melegueta Schum) Extract
por: Ilic, Nebojsa M., et al.
Publicado: (2014)

Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Aframomum melegueta Methanolic Seed Extract
por: Onoja, Samuel Okwudili, et al.
Publicado: (2014)

Antiviral activity of aframomum melegueta against severe acute respiratory syndrome coronaviruses type 1 and 2
por: Mahoney, Oneil, et al.
Publicado: (2022)

Antibacterial Activity of Defatted and Nondefatted Methanolic Extracts of Aframomum melegueta K. Schum. against Multidrug-Resistant Bacteria of Clinical Importance
por: Olajuyigbe, Olufunmiso Olusola, et al.
Publicado: (2020)

Trypanosoma brucei Inhibition by Essential Oils from Medicinal and Aromatic Plants Traditionally Used in Cameroon (Azadirachta indica, Aframomum melegueta, Aframomum daniellii, Clausena anisata, Dichrostachys cinerea and Echinops giganteus)
por: Ngahang Kamte, Stephane L., et al.
Publicado: (2017)

Protective Effect of Aframomum melegueta phenolics Against CCl(4)-Induced Rat Hepatocytes Damage; Role of Apoptosis and Pro-inflammatory Cytokines inhibition
por: El-Halawany, Ali M., et al.
Publicado: (2014)

The effects of Ficus carica on the activity of enzymes related to metabolic syndrome
por: Mopuri, Ramgopal, et al.
Publicado: (2017)

Anti-Th17 and anti-Th2 responses effects of hydro-ethanolic extracts of Aframomum melegueta, Khaya senegalensis and Xylopia aethiopica in hyperreactive onchocerciasis individuals’ peripheral blood mononuclear cells
por: Katawa, Gnatoulma, et al.
Publicado: (2022)

Aframomum melegueta Seed Extract with Standardized Content of 6-Paradol Reduces Visceral Fat and Enhances Energy Expenditure in Overweight Adults – A Randomized Double-Blind, Placebo-Controlled Clinical Study
por: Sudeep, Heggar Venkataramana, et al.
Publicado: (2022)

Spice-Derived Bioactive Ingredients: Potential Agents or Food Adjuvant in the Management of Diabetes Mellitus
por: Mohammed, Aminu, et al.
Publicado: (2018)

Turbina oblongata Protects Against Oxidative Cardiotoxicity by Suppressing Lipid Dysmetabolism and Modulating Cardiometabolic Activities Linked to Cardiac Dysfunctions
por: Erukainure, Ochuko L., et al.
Publicado: (2021)

Co-administration of sodium arsenite and ethanol: Protection by aqueous extract of Aframomum longiscapum seeds
por: Owumi, Solomon E., et al.
Publicado: (2012)

Optimisation of phenolic compounds and antioxidant activity extraction conditions of a roasted mix of Tetrapleura tetraptera (Schumach & Thonn.) and Aframomum citratum (C. Pereira) fruits using response surface methodology (RSM)
por: Manga, Eyenga, et al.
Publicado: (2020)

Phenolics Isolated from Aframomum meleguta Enhance Proliferation and Ossification Markers in Bone Cells
por: Abdel-Naim, Ashraf B., et al.
Publicado: (2017)

Soil-to-plant transfer of (40)K, (238)U and (232)Th and radiological risk assessment of selected mining sites in Nigeria
por: Orosun, Muyiwa Michael, et al.
Publicado: (2022)

Rapid Screening of Volatile Organic Compounds from Aframomum danielli Seeds Using Headspace Solid Phase Microextraction Coupled to Gas Chromatography Mass Spectrometry
por: George, Mosotho J., et al.
Publicado: (2018)

Anti-Helicobacter pylori and antiulcerogenic activity of Aframomum pruinosum seeds on indomethacin-induced gastric ulcer in rats
por: Kouitcheu Mabeku, Laure Brigitte, et al.
Publicado: (2017)

Characterization and Antioxidant Activity of Volatile Constituents from Different Parts of Aframomum danielli (Hook) K. Schum
por: Essien, Emmanuel E., et al.
Publicado: (2017)

Study on character association and path analysis in Korarima (Aframomum corrorima (Braun) Jansen) germplasms at Jimma Southwestern, Ethiopia
por: Kinfu, Simegn, et al.
Publicado: (2022)

Roles of Marine Macroalgae or Seaweeds and Their Bioactive Compounds in Combating Overweight, Obesity and Diabetes: A Comprehensive Review
por: Magwaza, S’thandiwe Nozibusiso, et al.
Publicado: (2023)

In Vitro Regeneration of Korarima (Aframomum corrorima (Braun) P. C. M. Jansen): A Threatened Spice and Medicinal Herb from Ethiopia
por: Hailu, Tilahun, et al.
Publicado: (2022)

Polyphenol-Rich Extracts of Xylopia and Aframomum Species Show Metabolic Benefits by Lowering Hepatic Lipid Accumulation in Diet-Induced Obese Mice
por: Nwakiban Atchan, Achille Parfait, et al.
Publicado: (2022)

Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction
por: Nguelefack-Mbuyo, Elvine Pami, et al.
Publicado: (2022)

Interaction of SARS-CoV-2 spike protein with angiotensin converting enzyme inhibitors and selected compounds from the chemical entities of biological interest
por: Aminu, Suleiman, et al.
Publicado: (2021)

Effects of butanol fraction of Ziziphus mucronata root ethanol extract on glucose homeostasis, serum insulin and other diabetes-related parameters in a murine model for type 2 diabetes
por: Ibrahim, Mohammed Auwal, et al.
Publicado: (2016)

Determination of patulin in products containing dried fruits by Enzyme‐Linked Immunosorbent Assay technique Patulin in dried fruits
por: Przybylska, Anna, et al.
Publicado: (2021)

In-vitro Studies on Calotropis procera Leaf Extracts as Inhibitors of Key Enzymes Linked to Diabetes Mellitus
por: Kazeem, Mutiu Idowu, et al.
Publicado: (2016)

Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines
por: Kuete, Victor, et al.
Publicado: (2014)

Bioactive compounds from Hypericum humifusum and Hypericum perfoliatum: inhibition potential of polyphenols with acetylcholinesterase and key enzymes linked to type-2 diabetes
por: Béjaoui, Afef, et al.
Publicado: (2017)

1-(5-Hydroxy-2,2,8,8-tetramethyl-2H,8H-pyrano[2,3-f]chromen-6-yl)ethanone
por: Pawar, Sunayna, et al.
Publicado: (2012)

Animal Models of Diabetic Neuropathy: Progress Since 1960s
por: Islam, Md. Shahidul
Publicado: (2013)

Molecular Regulations and Functions of the Transient Receptor Potential Channels of the Islets of Langerhans and Insulinoma Cells
por: Islam, Md. Shahidul
Publicado: (2020)

Inhibitory Potential against Digestive Enzymes Linked to Obesity and Type 2 Diabetes and Content of Bioactive Compounds in 20 Cultivars of the Peach Fruit Grown in Poland
por: Nowicka, Paulina, et al.
Publicado: (2018)

Inhibition of Key Enzymes Linked to Type 2 Diabetes and Sodium Nitroprusside Induced Lipid Peroxidation in Rats’ Pancreas by Phenolic Extracts of Avocado Pear Leaves and Fruit
por: Oboh, Ganiyu, et al.
Publicado: (2014)

The Contribution of Actinobacteria to the Degradation of Chlorinated Compounds: Variations in the Activity of Key Degradation Enzymes
por: Emelyanova, Elena V., et al.
Publicado: (2023)

Microsatellite marker-based genetic diversity assessment among exotic and native maize inbred lines of Bangladesh
por: Islam, Md. Amraul, et al.
Publicado: (2023)

Tetrahydrocannabinol-Rich Extracts From Cannabis Sativa L. Improve Glucose Consumption and Modulate Metabolic Complications Linked to Neurodegenerative Diseases in Isolated Rat Brains
por: Erukainure, Ochuko L., et al.
Publicado: (2020)

Inhibitory Potential of Turbinaria ornata against Key Metabolic Enzymes Linked to Diabetes
por: Unnikrishnan, P. S., et al.
Publicado: (2014)

Vanillin modulates activities linked to dysmetabolism in psoas muscle of diabetic rats
por: Salau, Veronica F., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ilpm2tgpc4suv28fmbkn9p7hup