Neuroprotective effects of ellagic acid on cuprizone-induced acute demyelination through limitation of microgliosis, adjustment of CXCL12/IL-17/IL-11 axis and restriction of mature oligodendrocytes apoptosis

Context: Ellagic acid (EA) is a natural phenol antioxidant with various therapeutic activities. However, the efficacy of EA has not been examined in neuropathologic conditions. Objective:In vivo neuroprotective effects of EA on cuprizone (cup)-induced demyelination were evaluated. Material and metho...

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Detalles Bibliográficos
Autores principales: Sanadgol, Nima, Golab, Fereshteh, Tashakkor, Zakiyeh, Taki, Nooshin, Moradi Kouchi, Samira, Mostafaie, Ali, Mehdizadeh, Mehdi, Abdollahi, Mohammad, Taghizadeh, Ghorban, Sharifzadeh, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130560/
https://www.ncbi.nlm.nih.gov/pubmed/28447514
http://dx.doi.org/10.1080/13880209.2017.1319867

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