In vitro schistosomicidal activity of the lignan (−)-6,6′-dinitrohinokinin (DNHK) loaded into poly(lactic-co-glycolic acid) nanoparticles against Schistosoma mansoni

Context: (−)-6,6′-Dinitrohinokinin (DNHK) display remarkable antiparasitic activity and was, therefore, incorporated into a nanoparticle formulation. Objective: Incorporation of DNHK in poly lactic-co-glycolic acid (PLGA) nanoparticles aiming to improve its biological activities. Materials and metho...

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Detalles Bibliográficos
Autores principales: Lima, Thaís C., Lucarini, Rodrigo, Luz, Priscilla P., de Faria, Emerson H., Marçal, Liziane, Magalhães, Lizandra G., Badoco, Fernanda R., Esperandim, Viviane R., Molina, Eduardo F., Laurentz, Rosangela S., Lima, Regiane G., Cunha, Wilson R., Bastos, Jairo K., Silva, Marcio L. Andrade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130564/
https://www.ncbi.nlm.nih.gov/pubmed/29172838
http://dx.doi.org/10.1080/13880209.2017.1405996

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