4-Nerolidylcatechol: apoptosis by mitochondrial mechanisms with reduction in cyclin D1 at G0/G1 stage of the chronic myelogenous K562 cell line

Context: 4-Nerolidylcatechol (4-NRC) has showed antitumor potential through apoptosis. However, its apoptotic mechanisms are still unclear, especially in leukemic cells. Objectives: To evaluate the cytotoxic potential of 4-NRC and its cell death pathways in p53-null K562 leukemic cells. Materials an...

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Detalles Bibliográficos
Autores principales: Benfica, Polyana Lopes, de Ávila, Renato Ivan, Rodrigues, Bruna dos Santos, Cortez, Alane Pereira, Batista, Aline Carvalho, Gaeti, Marilisa Pedroso Nogueira, Lima, Eliana Martins, Rezende, Kênnia Rocha, Valadares, Marize Campos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130688/
https://www.ncbi.nlm.nih.gov/pubmed/28644062
http://dx.doi.org/10.1080/13880209.2017.1311351

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