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Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands

[Image: see text] The complement system is our first line of defense against foreign pathogens, but when it is not properly regulated, complement is implicated in the pathology of several autoimmune and inflammatory disorders. Compstatin is a peptidic complement inhibitor that acts by blocking the c...

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Detalles Bibliográficos
Autores principales:	Mohan, Rohith R., Wilson, Mark, Gorham, Ronald D., Harrison, Reed E. S., Morikis, Vasilios A., Kieslich, Chris A., Orr, Asuka A., Coley, Alexis V., Tamamis, Phanourios, Morikis, Dimitrios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130793/ https://www.ncbi.nlm.nih.gov/pubmed/30221234 http://dx.doi.org/10.1021/acsomega.8b00606

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