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Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease

Chronic inflammation in inflammatory bowel disease (IBD) results from a breakdown of intestinal immune homeostasis and compromise of the intestinal barrier. Genome-wide association studies have identified over 200 genetic loci associated with risk for IBD, but the functional mechanisms of most of th...

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Detalles Bibliográficos
Autores principales:	Richard, Arianne C., Peters, James E., Savinykh, Natalia, Lee, James C., Hawley, Eric T., Meylan, Françoise, Siegel, Richard M., Lyons, Paul A., Smith, Kenneth G. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130856/ https://www.ncbi.nlm.nih.gov/pubmed/30199539 http://dx.doi.org/10.1371/journal.pgen.1007458

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