Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition

Viruses have long been implicated in the pathogenesis of autoimmunity, yet their contribution remains circumstantial partly due to the lack of well-documented information on infections prior to autoimmune disease onset. Here, we used the lymphocytic choriomeningitis virus (LCMV) as a model to mechan...

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Detalles Bibliográficos
Autores principales: Gonzalez-Quintial, Rosana, Nguyen, Anthony, Kono, Dwight H., Oldstone, Michael B. A., Theofilopoulos, Argyrios N., Baccala, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130858/
https://www.ncbi.nlm.nih.gov/pubmed/30199535
http://dx.doi.org/10.1371/journal.pone.0203118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130858/
https://www.ncbi.nlm.nih.gov/pubmed/30199535
http://dx.doi.org/10.1371/journal.pone.0203118

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