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Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition
Viruses have long been implicated in the pathogenesis of autoimmunity, yet their contribution remains circumstantial partly due to the lack of well-documented information on infections prior to autoimmune disease onset. Here, we used the lymphocytic choriomeningitis virus (LCMV) as a model to mechan...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130858/ https://www.ncbi.nlm.nih.gov/pubmed/30199535 http://dx.doi.org/10.1371/journal.pone.0203118 |