Cargando…

Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm

Human whipworm (Trichuris trichiura) infects approximately 1 in 15 people worldwide, representing the leading infectious cause of colitis and subsequent, inflammatory bowel disease (IBD). Current control measures focused on mass deworming have had limited success due to low drug efficacies. Vaccinat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Briggs, Neima, Wei, Junfei, Versteeg, Leroy, Zhan, Bin, Keegan, Brian, Damania, Ashish, Pollet, Jeroen, Hayes, Kelly S., Beaumier, Coreen, Seid, Christopher A., Leong, Jamie, Grencis, Richard K., Bottazzi, Maria Elena, Sastry, K. Jagannadha, Hotez, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130879/ https://www.ncbi.nlm.nih.gov/pubmed/30153307 http://dx.doi.org/10.1371/journal.ppat.1007273

Ejemplares similares

2257: Vaccine efficacy and immunogenicity of recombinant WAP and CAP-1 proteins in AKR mice
por: Briggs, Neima, et al.
Publicado: (2018)

Vaccination Against Whipworm: Identification of Potential Immunogenic Proteins in Trichuris muris Excretory/Secretory Material
por: Shears, Rebecca K., et al.
Publicado: (2018)

Identification, Characterization, and Structure of Tm16 from Trichuris muris
por: Liu, Zhuyun, et al.
Publicado: (2017)

Testing parasite ‘intimacy’: the whipworm Trichuris muris in the European house mouse hybrid zone
por: , Wasimuddin, et al.
Publicado: (2016)

Immunoregulatory molecules secreted by Trichuris muris
por: Bancroft, Allison J., et al.
Publicado: (2021)

Trickle infection and immunity to Trichuris muris
por: Glover, Maya, et al.
Publicado: (2019)

Trichuris muris: a model of gastrointestinal parasite infection
por: Klementowicz, Joanna E., et al.
Publicado: (2012)

Trichuris muris and comorbidities – within a mouse model context
por: Hayes, Kelly S., et al.
Publicado: (2021)

Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response
por: Wei, Junfei, et al.
Publicado: (2017)

Advancing a multivalent ‘Pan-anthelmintic’ vaccine against soil-transmitted nematode infections
por: Zhan, Bin, et al.
Publicado: (2014)

Changes in the mucosal barrier during acute and chronic Trichuris muris infection
por: Hasnain, S Z, et al.
Publicado: (2011)

Extracellular vesicles induce protective immunity against Trichuris muris
por: Shears, R. K., et al.
Publicado: (2018)

Genome and transcriptome of the porcine whipworm Trichuris suis
por: Jex, Aaron R, et al.
Publicado: (2014)

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier
por: Hasnain, Sumaira Z., et al.
Publicado: (2012)

Functional Characterization of the Oxantel-Sensitive Acetylcholine Receptor from Trichuris muris
por: Hansen, Tina V. A., et al.
Publicado: (2021)

Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis
por: Vejzagić, Nermina, et al.
Publicado: (2015)

The Failure of Thymol to Expel Whipworms (Trichuris Depressiuscula) from Dogs
por: Stiles, Ch. Wardell, et al.
Publicado: (1902)

Trichuris WAP and CAP proteins: Potential whipworm vaccine candidates?
por: Wainwright, Eleanor, et al.
Publicado: (2022)

Glucose Absorption by the Bacillary Band of Trichuris muris
por: Hansen, Tina V. A., et al.
Publicado: (2016)

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion
por: Hasnain, Sumaira Z., et al.
Publicado: (2017)

The role of sex hormones in the development of Th2 immunity in a gender-biased model of Trichuris muris infection
por: Hepworth, Matthew R, et al.
Publicado: (2010)

The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections
por: Briggs, Neima, et al.
Publicado: (2016)

Severe whipworm (Trichuris spp.) infection in the hamadryas baboon (Papio hamadryas)
por: EO, Kyung-Yeon, et al.
Publicado: (2018)

Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota
por: Cooper, Philip, et al.
Publicado: (2013)

Characterization of the Complete Mitochondrial Genome of a Whipworm Trichuris skrjabini (Nematoda: Trichuridae)
por: Ahmad, Awais Ali, et al.
Publicado: (2019)

Chronic Trichuris muris infection causes neoplastic change in the intestine and exacerbates tumour formation in APC min/+ mice
por: Hayes, Kelly S., et al.
Publicado: (2017)

Trichuris muris research revisited: a journey through time
por: HURST, REBECCA J. M., et al.
Publicado: (2013)

Whipworm secretions and their roles in host-parasite interactions
por: Shears, Rebecca K., et al.
Publicado: (2022)

Development of caecaloids to study host–pathogen interactions: new insights into immunoregulatory functions of Trichuris muris extracellular vesicles in the caecum
por: Duque-Correa, María A., et al.
Publicado: (2020)

Lymphocyte Migration Inhibition Response in Trichuris muris Infected and Vaccinated Mice
por: Gaherwal, S, et al.
Publicado: (2011)

An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro
por: Hurst, Rebecca JM, et al.
Publicado: (2014)

Trichuris muris egg-hatching assay for anthelminthic drug discovery and characterization
por: Schärer, Anastasia, et al.
Publicado: (2023)

Mitogenomics and Evolutionary History of Rodent Whipworms (Trichuris spp.) Originating from Three Biogeographic Regions
por: Petružela, Jan, et al.
Publicado: (2021)

A role for the pattern recognition receptor Nod2 in promoting recruitment of CD103(+) Dendritic Cells to the colon in response to Trichuris muris infection
por: Bowcutt, Rowann, et al.
Publicado: (2014)

Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae
por: Wimmersberger, David, et al.
Publicado: (2013)

Metabolomes and Lipidomes of the Infective Stages of the Gastrointestinal nematodes, Nippostrongylus brasiliensis and Trichuris muris
por: Yeshi, Karma, et al.
Publicado: (2020)

Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation
por: Levison, Scott E, et al.
Publicado: (2013)

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance
por: Houlden, Ashley, et al.
Publicado: (2015)

A genome-scale metabolic model of parasitic whipworm
por: Bay, Ömer F., et al.
Publicado: (2023)

Hidden Population Structure and Cross-species Transmission of Whipworms (Trichuris sp.) in Humans and Non-human Primates in Uganda
por: Ghai, Ria R., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_nn48qt7j2044qm27bekjb03q6j