Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α(4)β(7)

The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synthetic peptides derived from HIV and SIV gp120 bind...

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Detalles Bibliográficos
Autores principales: Lertjuthaporn, Sakaorat, Cicala, Claudia, Van Ryk, Donald, Liu, Matthew, Yolitz, Jason, Wei, Danlan, Nawaz, Fatima, Doyle, Allison, Horowitch, Brooke, Park, Chung, Lu, Shan, Lou, Yang, Wang, Shixia, Pan, Ruimin, Jiang, Xunqing, Villinger, Francois, Byrareddy, Siddappa N., Santangelo, Philip J., Morris, Lynn, Wibmer, Constantinos Kurt, Biris, Kristin, Mason, Rosemarie D., Gorman, Jason, Hiatt, Joseph, Martinelli, Elena, Roederer, Mario, Fujikawa, Dai, Gorini, Giacomo, Franchini, Genoveffa, Arakelyan, Anush, Ansari, Aftab A., Pattanapanyasat, Kovit, Kong, Xiang-Peng, Fauci, Anthony S., Arthos, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130882/
https://www.ncbi.nlm.nih.gov/pubmed/30153309
http://dx.doi.org/10.1371/journal.ppat.1007278

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