Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction

The phosphorylation of JNK is known to induce insulin resistance in insulin target tissues. The inhibition of JNK-JIP1 interaction, which interferes JNK phosphorylation, becomes a potential target for drug development of type 2 diabetes. To discover the inhibitors of JNK-JIP1 interaction, we screene...

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Detalles Bibliográficos
Autores principales: Li, Yi, Jung, Nan-Young, Yoo, Jae Cheal, Kim, Yul, Yi, Gwan-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131017/
https://www.ncbi.nlm.nih.gov/pubmed/29129046
http://dx.doi.org/10.4062/biomolther.2017.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131017/
https://www.ncbi.nlm.nih.gov/pubmed/29129046
http://dx.doi.org/10.4062/biomolther.2017.123

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