Cargando…

Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction

The phosphorylation of JNK is known to induce insulin resistance in insulin target tissues. The inhibition of JNK-JIP1 interaction, which interferes JNK phosphorylation, becomes a potential target for drug development of type 2 diabetes. To discover the inhibitors of JNK-JIP1 interaction, we screene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yi, Jung, Nan-Young, Yoo, Jae Cheal, Kim, Yul, Yi, Gwan-Su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131017/ https://www.ncbi.nlm.nih.gov/pubmed/29129046 http://dx.doi.org/10.4062/biomolther.2017.123

Ejemplares similares

Cardioselective versus Non-Cardioselective Beta-Blockers and Outcomes in Patients with Atrial Fibrillation and Chronic Obstructive Pulmonary Disease
por: Vlachopoulou, Dimitra, et al.
Publicado: (2023)

An evaluation of the effects of nonselective and cardioselective β-blockers on wound healing in Sprague Dawley rats
por: Raut, Sanket B., et al.
Publicado: (2012)

The safety of cardioselective β(1)-blockers in asthma: literature review and search of global pharmacovigilance safety reports
por: Bennett, Miriam, et al.
Publicado: (2021)

Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis
por: Vaishnav, Mahesh, et al.
Publicado: (2011)

PVC Membrane Sensors for Potentiometric Determination of Acebutolol
por: Mostafa, Gamal Abdel-Hafiz, et al.
Publicado: (2007)

Cardioselective peripheral noradrenergic deficiency in Lewy body synucleinopathies
por: Lamotte, Guillaume, et al.
Publicado: (2020)

Targeting JNK-interacting protein 1 (JIP1) sensitises osteosarcoma to doxorubicin
por: De Boer, Jantine Posthuma, et al.
Publicado: (2012)

Syd/JIP3 and JNK Signaling Are Required for Myonuclear Positioning and Muscle Function
por: Schulman, Victoria K., et al.
Publicado: (2014)

LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol
por: Rakibe, Uday, et al.
Publicado: (2018)

Reassembly of JIP1 Scaffold Complex in JNK MAP Kinase Pathway Using Heterologous Protein Interactions
por: Moon, Jiyoung, et al.
Publicado: (2014)

Acute and Chronic Hyperglycemia Elicit JIP1/JNK-Mediated Endothelial Vasodilator Dysfunction of Retinal Arterioles
por: Hein, Travis W., et al.
Publicado: (2016)

Colocalization and Interaction Study of Neuronal JNK3, JIP1, and β-Arrestin2 Together with PSD95
por: Musi, Clara Alice, et al.
Publicado: (2022)

Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases
por: Cason, Sydney E., et al.
Publicado: (2023)

CTRP3 alleviates cardiac ischemia/reperfusion injury via LAMP1/JIP2/JNK signaling pathway
por: Song, Yanbin, et al.
Publicado: (2022)

Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids
por: Al-Ghamdi, Ali F, et al.
Publicado: (2012)

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
por: Gowrishankar, Swetha, et al.
Publicado: (2021)

The interaction of Kinesin-1 with its adaptor protein JIP1 can be regulated via proteins binding to the JIP1-PTB domain
por: Satake, Tomoko, et al.
Publicado: (2013)

Anti-inflammatory Effect of Glucagon Like Peptide-1 Receptor Agonist, Exendin-4, through Modulation of IB1/JIP1 Expression and JNK Signaling in Stroke
por: Kim, Soojin, et al.
Publicado: (2017)

Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride
por: Al-Mohaimeed, Amal M., et al.
Publicado: (2023)

Arf6, JIP3, and dynein shape and mediate macropinocytosis
por: Williamson, Chad D., et al.
Publicado: (2019)

miR-126-5p by direct targeting of JNK-interacting protein-2 (JIP-2) plays a key role in Theileria-infected macrophage virulence
por: Haidar, Malak, et al.
Publicado: (2018)

The JIP1 Scaffold Protein Regulates Axonal Development in Cortical Neurons
por: Dajas-Bailador, Federico, et al.
Publicado: (2008)

Cargo of Kinesin Identified as Jip Scaffolding Proteins and Associated Signaling Molecules
por: Verhey, Kristen J., et al.
Publicado: (2001)

Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1–MEK–JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop
por: Song, Jae J., et al.
Publicado: (2005)

Beta‐blockers for hypertension
por: Wiysonge, Charles S, et al.
Publicado: (2017)

Beta-blockers in sepsis
por: Singer, Mervyn
Publicado: (2019)

Beta Blockers and Melanoma
por: Vojvodic, Aleksandra, et al.
Publicado: (2019)

An unusual toxicity with beta blocker and calcium channel blocker
por: Anand, Vijay, et al.
Publicado: (2015)

Bibliometric Properties of Placebo Literature From the JIPS Database: A Descriptive Study
por: Weimer, Katja, et al.
Publicado: (2022)

JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton
por: Rafiq, N. M., et al.
Publicado: (2022)

JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport
por: Celestino, Ricardo, et al.
Publicado: (2022)

JNK interacting protein 1 (JIP-1) protects LNCaP prostate cancer cells from growth arrest and apoptosis mediated by 12-0-tetradecanoylphorbol-13-acetate (TPA)
por: Ikezoe, T, et al.
Publicado: (2004)

Impact of Angiotensin Receptor Blockers, Beta Blockers, Calcium Channel Blockers and Thiazide Diuretics on Survival of Ovarian Cancer Patients
por: Cho, Min Ae, et al.
Publicado: (2020)

Perioperative use of beta-blockers
por: Priebe, Hans-Joachim
Publicado: (2009)

Beta-blockers in liver cirrhosis
por: Giannelli, Valerio, et al.
Publicado: (2014)

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
por: Fu, Meng-meng, et al.
Publicado: (2013)

Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology
por: Gowrishankar, Swetha, et al.
Publicado: (2017)

Doublecortin and JIP3 are neural-specific counteracting regulators of dynein-mediated retrograde trafficking
por: Fu, Xiaoqin, et al.
Publicado: (2022)

Beta-blocker Therapy at Discharge in Patients with Acute Heart Failure and Atrial Fibrillation
por: Ahn, Min-Soo, et al.
Publicado: (2020)

T-Type Ca(2+) Channel Blocker, KYS05090 Induces Autophagy and Apoptosis in A549 Cells through Inhibiting Glucose Uptake
por: Rim, Hong-Kun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2hnvojt1o5i8hf0d653jt9fbq1