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Intestinal epithelial Toll-Like Receptor 4 Prevents Metabolic Syndrome by Regulating Interactions Between Microbes and Intestinal Epithelial Cells in Mice

Little is known about the pathogenesis of metabolic syndrome, although Toll-like receptor 4 (TLR4) has been implicated. We investigated whether TLR4 in the intestinal epithelium regulates metabolic syndrome by coordinating interactions between the luminal microbiota and host genes that regulate meta...

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Detalles Bibliográficos
Autores principales: Lu, Peng, Sodhi, Chhinder P., Yamaguchi, Yukihiro, Jia, Hongpeng, Prindle, Thomas, Fulton, William B., Vikram, Amit, Bibby, Kyle J., Morowitz, Michael J., Hackam, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131112/
https://www.ncbi.nlm.nih.gov/pubmed/29363671
http://dx.doi.org/10.1038/mi.2017.114