Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers

OBJECTIVES: Our objective was to develop population pharmacokinetic (PK) models for ceftazidime and avibactam in the plasma and epithelial lining fluid (ELF) of healthy volunteers and to compare ELF concentrations to plasma PK/pharmacodynamic (PD) targets. METHODS: Plasma and ELF population PK model...

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Detalles Bibliográficos
Autores principales: Dimelow, Richard, Wright, James G., MacPherson, Merran, Newell, Paul, Das, Shampa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131119/
https://www.ncbi.nlm.nih.gov/pubmed/30054895
http://dx.doi.org/10.1007/s40268-018-0241-0

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