Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3

Runx2 and Sp7 are essential transcription factors for osteoblast differentiation. However, the molecular mechanisms responsible for the proliferation of osteoblast progenitors remain unclear. The early onset of Runx2 expression caused limb defects through the Fgfr1–3 regulation by Runx2. To investig...

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Detalles Bibliográficos
Autores principales: Kawane, Tetsuya, Qin, Xin, Jiang, Qing, Miyazaki, Toshihiro, Komori, Hisato, Yoshida, Carolina Andrea, Matsuura-Kawata, Viviane Keiko dos Santos, Sakane, Chiharu, Matsuo, Yuki, Nagai, Kazuhiro, Maeno, Takafumi, Date, Yuki, Nishimura, Riko, Komori, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131145/
https://www.ncbi.nlm.nih.gov/pubmed/30202094
http://dx.doi.org/10.1038/s41598-018-31853-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131145/
https://www.ncbi.nlm.nih.gov/pubmed/30202094
http://dx.doi.org/10.1038/s41598-018-31853-0

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