APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress

Two coding sequence variants (G1 and G2) of Apolipoprotein L1 (APOL1) gene have been implicated as a higher risk factor for chronic kidney diseases (CKD) in African Americans when compared with European Americans. Previous studies have suggested that the APOL1 G1 and G2 variant proteins are more tox...

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Detalles Bibliográficos
Autores principales: Wen, Hongxiu, Kumar, Vinod, Lan, Xiqian, Shoshtari, Seyedeh Shadafarin Marashi, Eng, Judith M., Zhou, Xiaogang, Wang, Fang, Wang, Haichao, Skorecki, Karl, Xing, Guolan, Wu, Guisheng, Luo, Huairong, Malhotra, Ashwani, Singhal, Pravin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131197/
https://www.ncbi.nlm.nih.gov/pubmed/29967295
http://dx.doi.org/10.1042/BSR20171713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131197/
https://www.ncbi.nlm.nih.gov/pubmed/29967295
http://dx.doi.org/10.1042/BSR20171713

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