Cargando…
Increased inflammation and brain glutamate define a subtype of depression with decreased regional homogeneity, impaired network integrity, and anhedonia
Combined increases in peripheral inflammation and brain glutamate may identify a subtype of depression with distinct neuroimaging signatures. Two contrasting subgroups of depressed subjects—with and without combined elevations in plasma C-reactive protein (CRP) and basal ganglia glutamate (high and...
Autores principales: | Haroon, Ebrahim, Chen, Xiangchuan, Li, Zhihao, Patel, Thrusharth, Woolwine, Bobbi J., Hu, Xiaoping P., Felger, Jennifer C., Miller, Andrew H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131242/ https://www.ncbi.nlm.nih.gov/pubmed/30202011 http://dx.doi.org/10.1038/s41398-018-0241-4 |
Ejemplares similares
-
Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study
por: Bekhbat, Mandakh, et al.
Publicado: (2022) -
Correction to: Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study
por: Bekhbat, Mandakh, et al.
Publicado: (2022) -
Kynurenines increase MRS metabolites in basal ganglia and decrease resting-state connectivity in frontostriatal reward circuitry in depression
por: Chen, Xiangchuan, et al.
Publicado: (2021) -
Transcriptomic Signatures of Psychomotor Slowing in Peripheral Blood of Depressed Patients: Evidence for Immunometabolic Reprogramming
por: Bekhbat, Mandakh, et al.
Publicado: (2021) -
Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression
por: Haroon, E, et al.
Publicado: (2016)