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SMRT-Cappable-seq reveals complex operon variants in bacteria

Current methods for genome-wide analysis of gene expression require fragmentation of original transcripts into small fragments for short-read sequencing. In bacteria, the resulting fragmented information hides operon complexity. Additionally, in vivo processing of transcripts confounds the accurate...

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Detalles Bibliográficos
Autores principales:	Yan, Bo, Boitano, Matthew, Clark, Tyson A., Ettwiller, Laurence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131387/ https://www.ncbi.nlm.nih.gov/pubmed/30201986 http://dx.doi.org/10.1038/s41467-018-05997-6

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