HCV-associated exosomes promote myeloid-derived suppressor cell expansion via inhibiting miR-124 to regulate T follicular cell differentiation and function

Virus-infected cells can regulate non-permissive bystander cells, but the precise mechanisms remain incompletely understood. Here we report that this process can be mediated by transfer of viral RNA-loaded exosomes shed from infected cells to myeloid-derived suppressor cells (MDSCs), which in turn r...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Cao, Dechao, Wang, Ling, Zhao, Juan, Nguyen, Lam Nhat, Dang, Xindi, Ji, Yingjie, Wu, Xiao Y., Morrison, Zheng D., Xie, Qian, El Gazzar, Mohamed, Ning, Shunbin, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131392/
https://www.ncbi.nlm.nih.gov/pubmed/30210805
http://dx.doi.org/10.1038/s41421-018-0052-z

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