Cargando…

Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem

The burden of cardiovascular and metabolic diseases is increasing with every year. Although the management of these conditions has improved greatly over the years, it is still far from perfect. With all of this in mind, there is a need for new methods of prophylaxis and treatment. Coenzyme Q10 (CoQ1...

Descripción completa

Detalles Bibliográficos
Autores principales: Zozina, Vladlena I., Covantev, Serghei, Goroshko, Olga A., Krasnykh, Liudmila M., Kukes, Vladimir G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131403/
https://www.ncbi.nlm.nih.gov/pubmed/29663894
http://dx.doi.org/10.2174/1573403X14666180416115428
_version_ 1783354096700358656
author Zozina, Vladlena I.
Covantev, Serghei
Goroshko, Olga A.
Krasnykh, Liudmila M.
Kukes, Vladimir G.
author_facet Zozina, Vladlena I.
Covantev, Serghei
Goroshko, Olga A.
Krasnykh, Liudmila M.
Kukes, Vladimir G.
author_sort Zozina, Vladlena I.
collection PubMed
description The burden of cardiovascular and metabolic diseases is increasing with every year. Although the management of these conditions has improved greatly over the years, it is still far from perfect. With all of this in mind, there is a need for new methods of prophylaxis and treatment. Coenzyme Q10 (CoQ10) is an essential compound of the human body. There is growing evidence that COQ10 is tightly linked to cardiometabolic disorders. Its supplementation can be useful in a variety of chronic and acute disorders. This review analyses the role of COQ10 in hypertension, ischemic heart disease, myocardial infarction, heart failure, viral myocarditis, cardiomyopathies, cardiac toxicity, dyslipidemia, obesity, type 2 diabetes mellitus, metabolic syndrome, cardiac procedures and resuscitation.
format Online
Article
Text
id pubmed-6131403
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Bentham Science Publishers
record_format MEDLINE/PubMed
spelling pubmed-61314032019-08-01 Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem Zozina, Vladlena I. Covantev, Serghei Goroshko, Olga A. Krasnykh, Liudmila M. Kukes, Vladimir G. Curr Cardiol Rev Article The burden of cardiovascular and metabolic diseases is increasing with every year. Although the management of these conditions has improved greatly over the years, it is still far from perfect. With all of this in mind, there is a need for new methods of prophylaxis and treatment. Coenzyme Q10 (CoQ10) is an essential compound of the human body. There is growing evidence that COQ10 is tightly linked to cardiometabolic disorders. Its supplementation can be useful in a variety of chronic and acute disorders. This review analyses the role of COQ10 in hypertension, ischemic heart disease, myocardial infarction, heart failure, viral myocarditis, cardiomyopathies, cardiac toxicity, dyslipidemia, obesity, type 2 diabetes mellitus, metabolic syndrome, cardiac procedures and resuscitation. Bentham Science Publishers 2018-08 2018-08 /pmc/articles/PMC6131403/ /pubmed/29663894 http://dx.doi.org/10.2174/1573403X14666180416115428 Text en © 2018 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Zozina, Vladlena I.
Covantev, Serghei
Goroshko, Olga A.
Krasnykh, Liudmila M.
Kukes, Vladimir G.
Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem
title Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem
title_full Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem
title_fullStr Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem
title_full_unstemmed Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem
title_short Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem
title_sort coenzyme q10 in cardiovascular and metabolic diseases: current state of the problem
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131403/
https://www.ncbi.nlm.nih.gov/pubmed/29663894
http://dx.doi.org/10.2174/1573403X14666180416115428
work_keys_str_mv AT zozinavladlenai coenzymeq10incardiovascularandmetabolicdiseasescurrentstateoftheproblem
AT covantevserghei coenzymeq10incardiovascularandmetabolicdiseasescurrentstateoftheproblem
AT goroshkoolgaa coenzymeq10incardiovascularandmetabolicdiseasescurrentstateoftheproblem
AT krasnykhliudmilam coenzymeq10incardiovascularandmetabolicdiseasescurrentstateoftheproblem
AT kukesvladimirg coenzymeq10incardiovascularandmetabolicdiseasescurrentstateoftheproblem