Characterization of the hypersensitive response‐like cell death phenomenon induced by targeting antiviral lectin griffithsin to the secretory pathway

Griffithsin (GRFT) is an antiviral lectin, originally derived from a red alga, which is currently being investigated as a topical microbicide to prevent transmission of human immunodeficiency virus (HIV). Targeting GRFT to the apoplast for production in Nicotiana benthamiana resulted in necrotic sym...

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Detalles Bibliográficos
Autores principales: Kim, Bo Min, Lotter‐Stark, Hester Catharina Therese, Rybicki, Edward P., Chikwamba, Rachel K., Palmer, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131415/
https://www.ncbi.nlm.nih.gov/pubmed/29509998
http://dx.doi.org/10.1111/pbi.12917

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